Dermatology
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Aspirin: Good for the Heart, Better for the Pain
Although several other studies have examined the relationship between analgesic use and blood pressure, this report from the Nurses Health Study is the first prospective look at all 3 classes of over-the-counter analgesics. -
A Cutting Edge Question
This randomized controlled study compared surgery vs nocturnal wrist splints in 176 patients with idiopathic carpal tunnel syndrome. -
Do Statins Really Cause Muscle Symptoms?
Phillips et al have demonstrated that increasing muscular aches and pains often associated with decreased exercise tolerance may, in fact, be due to statin therapy even in patients with normal CPK determinations. -
‘Mad Deer Disease’: Another Reason to Become a Vegetarian?
The emergence of chronic wasting disease, a transmissible spongiform encephalopathy in North American cervids, raises concern about potential transmission to humans, as has occurred elsewhere with bovine spongiform encephalopathy and vCJD. -
Clinical Briefs in Primary Care Supplement
MRC/BHF Heart Protection Study of Antioxidant Vitamin Supplementation in 20,536 High-Risk Individuals; Prolonged Erections Produced by Dihydrocodeine & Sildenafil; Effect of Magnesium Supplementation of Blood Pressure; Homocysteine-Lowering Therapy with Folic Acid, Vitamins, and Clinical Outcome after Percutaneous Coronary Intervention; Effect of Cataract Surgery on Motor Vehicle Accidents in Older Adults; Inflammatory Biomarkers, Hormone Replacement Therapy, and Incident Coronary Heart Disease -
Pharmacology Watch: High-Dose Rofecoxib Confirmed Prothrombotic, Study Shows
Debate over the cardiovascular effects of COX-2 inhibitors has raged for more than a year since a special communication was published in JAMA last August suggesting an increase in cardiovascular events with rofecoxib (Vioxx). Now a large retrospect, the cohort study from the Tennessee Medicaid program seems to confirm the prothrombotic effects of rofecoxib, at least in high dose. -
When to Order a Sleep Study and How to Read the Report: Part II
Understanding the information provided in a sleep study report and knowing how to use it is crucial for accurate diagnosis and effective treatment. The combined information from the sleep history and the sleep report allows diagnosis of all sleep disorders. -
Clinical Briefs in Primary Care
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Clinical Briefs in Primary Care
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Yoga and Vasomotor Symptoms: Does a Meditative Movement Practice Improve Menopausal Symptoms?
Synopsis: In a randomized controlled trial, the implementation of a regular yoga practice was not shown to significantly improve vasomotor symptom frequency or bother at 6 and 12 weeks. However, it was associated with a significant improvement in Insomnia Severity Index.