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Tadalafil, Eli Lillyâs blockbuster drug for erectile dysfunction, has now been approved to treat signs and symptoms of benign prostatic hyperplasia. Tadalafil is the first drug of its class to be approved for this indication.
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From a large cohort of women followed prospectively and with an adjunct meta-analysis of existing evaluable studies, a clearly demonstrated, nearly universal (i.e., across tumor types) incremental increase in cancer incidence was observed with advancing height.
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A newly developed instrument to measure brief physical activity counseling in primary care demonstrates that physicians need to do a better job.
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Recent retrospective studies in Europe have created concern because of an observed increased risk of cancer (hazard ratio = 1.55) in users of insulin glargine (GLAR) compared to nonusers.
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The authors conclude that patients with coronary stents undergoing an invasive procedure are at high risk of perioperative cardiovascular and bleeding complications, and that these are associated with a high mortality.
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Vaccination has dramatically reduced the number of cases of chickenpox, measles, polio, mumps, and pertussis treated in primary care settings. Antibiotic treatment of streptococcal pharyngitis has reduced the number of cases of rheumatic fever. As a result, there are generations of physicians who have never encountered patients with these diseases. These diseases are often relegated to the historical section of general medical textbooks. However, recent isolated outbreaks in adults as well as children have brought these diseases back into the forefront for primary care providers.
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The authors conclude that this large observational study suggests ACEI or ARB therapy is associated with an improved survival and a lower risk of cardiovascular events in patients with aortic stenosis.
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A kinase inhibitor for late-stage melanoma and its companion diagnostic test have been approved by the FDA.
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Both urgency and bladder pain can lead to nocturia in patients with interstitial cystitis.
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For many patients with moderate- severe chronic obstructive pulmonary disease, acute exacerbations (AECOPD) are highly problematic.
