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In a meta-analysis of multiple prospective cohort studies, the lowest vitamin D metabolite (25-hydroxyvitamin D) quintile was associated with increased all-cause mortality, cardiovascular mortality, and cancer mortality.
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A second inhalation rapid human insulin has been approved by the FDA. The first inhaled insulin (Exubera) was approved in 2006 and was withdrawn from the market by Pfizer due to low acceptance and poor sales after about 13 months on the market
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In a study of young adults, attempted physician deception to obtain a pharmaceutical drug was found to exist in a limited manner along with general characteristics of those patients who may divert medications.
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The first fixed-dose combination drug product has been approved for the treatment of chronic hepatitis C virus (HCV) genotype 1 infection. The combination contains a previously approved HCV nucleotide analog NS5B polymerase inhibitor, sofosbuvir (SOF), and a NS5A inhibitor, ledipasvir (LDV). This represents the first treatment option for HCV genotype 1 that does not require ribavirin or interferon.
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The ECG in the Figure was obtained from a patient with new-onset chest pain. What is the likely culprit artery? Is this patient a good candidate for acute reperfusion?
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Sometimes despite best efforts on the part of the clinician and the type 2 diabetes patient, A1c goals are not met. Although in some circumstances the underlying limitation to goal attainment is readily discernible (hypoglycemic episodes, non-compliance, medication misadministration, excessive weight gain, other adverse effects), it is not always so clear.
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Szapary PO, Bloedon LT. Flaxseed and flaxseed oil in the management of hypercholesterolemia. Part 1. Altern Med Alert 2001;12:140-143.
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Marcolina ST. The use of psyllium and soy for hypercholesterolemia. Altern Med Alert 2001;12:136-140.
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La Puma J. Diet, lifestyle and Type 2 diabetes in women. Altern Med Alert 2001;12:144.
