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Dermatology

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  • Pharmacology Update: Fentanyl Sublingual Tablets (Abstral®) CII

    The fda has approved a new formulation of fentanyl for the management of breakthrough pain in cancer patients.
  • Is Lower BP Always Really Better?

    The risk of future cardiovascular events in patients with an acute coronary syndrome (ACS) was lowest when the BP was in the range of approximately 130-140 mmHg systolic and 80-90 mm Hg diastolic and became highest as the blood pressure became lower; in fact, a blood pressure less than 110/70 mm Hg may actually be dangerous.
  • Early to Bed? Maybe Not Such a Good Idea

    Brief behavioral intervention significantly relieved insomnia in a group of older adults.
  • Clinical Briefs by Louis Kuritzky, MD

    It has been recognized for more than a decade that most patients with IBS have abnormal lactulose hydrogen breath tests results, consistent with small bowel bacterial overgrowth.
  • ECG Review: History Is Everything

    The ECG shows sinus rhythm at 85/minute. The PR interval is normal. The QRS duration is upper normal (half a large box, but not more) and the QT interval is upper normal (about half the R-R interval, with a QTc ≈ 0.44 second).
  • Acetaminophen Toxicity

    In June 2009, the advisors of the U.S. Food and Drug Administration recommended lowering the maximum dose of over-the counter acetaminophen, which is the key ingredient in such popular products such as Tylenol and Excedrin. The advisors were concerned that severe liver damage and even death can result from excessive ingestion of acetaminophen, which many consumers consider to be easier on the stomach than other medications and safe.
  • Symptoms and Asymptote: Echinacea and Colds

    The results of this well-done study suggest that a specific formulation of echinacea may offer modest benefit to people with the common cold, but that such benefit is statistically, and likely clinically, insignificant. Data from the trial relating to physician-patient interaction and clinical response have yet to be published.
  • An Honest Response — Placebos and IBS

    Findings of this ground-breaking randomized controlled trial suggest that patients with irritable bowel syndrome who receive treatment with placebo tablets, and who are fully aware that they are taking a placebo, have significantly greater relief of symptoms compared with patients who receive no treatment at all. Accessing the placebo effect may not require deception at all.
  • Glucosamine Sulfate for Osteoarthritis

    Glucosamine sulfate continues to grow in popularity as a treatment for osteoarthritis. Global sales reached almost $2 billion in 2008, an increase of 60 percent over the previous five years.
  • Now How Much Vitamin D and Calcium Should We Take?

    An evaluation of medical research by the IOM establishes new RDAs for vitamin D (600-800 IU) and calcium (700-1300 milligrams).