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Mitochondrial oxidative stress and damage is connected to neuronal cell death and behavioral outcomes after TBI. Antioxidant treatment with the amide form of N-acetylcsyteine, which has central nervous system (CNS) bioavailability, was shown to improve markers of damage and cognitive function in rats when provided by intraperitoneal injection post experimental TBI.
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This randomized, parallel group study over 12 months found greater weight and cardiovascular risk benefits in obese adults eating a low-carbohydrate diet vs a low-fat diet.
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A polysaccharide-rich extract of turmeric rhizome provided benefits in people with knee osteoarthritis.
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This issue of Primary Care Reports concludes the series on headache disorders. Part I covered headache history, physical examination, diagnostic testing, and differential. Part II addresses common headache diagnoses and their management.
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Efficacy of once-daily insulin, aldo-sterone use in heart failure, erectile dysfunction Clinical Practice Guidelines, and FDA Actions.
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The U. S. Surgeon General has advised women not to drink if they become pregnant, plan to become pregnant, or are at risk of becoming pregnant. Innocent children suffer the consequences of physical, mental, and behavioral manifestations that can extend into adulthood. Since fetal alcohol syndrome is 100% preventable, the primary care physician needs to be vigilant and diligent in the education of female adolescents and women of childbearing age.
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Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
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Taking data from a large cohort being followed prospectively, the authors of this trial found that a dietary pattern disturbingly similar to our "Western-style" way of eating is significantly associated with a greater risk for self-reported depression at 5 years of follow-up when compared to an eating pattern that more closely mimics the Mediterranean- or Asian-style diet.