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The consequences of vitamin b12 (B12) deficiency most commonly include neurologic (CNS and peripheral nervous system) and hematologic (megaloblastic anemia).
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A new drug for the treatment of neurogenic orthostatic hypotension (NOH) has been approved by the FDA under its accelerated approval program. Droxidopa is a prodrug to norepinephrine.
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This study demonstrates an association between the use of hospitalists by a hospital and a reduction in 30-day excess readmission rates for heart failure, acute myocardial infarction, and pneumonia.
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Historically, men with high-risk prostate cancer were believed to have low survival rates after definitive treatment with either surgery or radiation. However, long-term results of dose-escalated radiotherapy of doses ≥ 75.6 Gy, along with long-term androgen deprivation therapy (ADT), demonstrate 5-year survival rate of 92%, 5-year biochemical control rate of 82%, and symptomatic local failure rate of 0%. Death from prostate cancer was only 5.5% at 10 years in men treated with high-dose radiation therapy and ADT.
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In a study of men in the Veterans Affairs health care system with low serum testosterone levels, the use of testosterone therapy was associated with an increased risk of mortality, myocardial infarction, or ischemic stroke.
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The use of dabigatran in patients with mechanical heart valves compared with patients receiving warfarin was associated with increased rates of thromboembolic and bleeding complications, thus demonstrating no benefit and an excess risk.
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RSV occurs primarily in the winter months in the United States and is a cause of significant morbidity and mortality, particularly in the very young and very old.
