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Procedural sedation and analgesia (PSA) has been provided to children in the emergency department for decades. When patients are evaluated properly, and adequate equipment, personnel, and medications are utilized, effective and safe PSA is delivered by the emergency physician, whether in a university or community setting, over a wide range of ages, and with a broad selection of medications.
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Current American College of Cardiology/ American Heart Association (ACC/AHA) Guidelines recommend withholding non-steroidal anti-inflammatory drugs (NSAIDs) from patients who have suffered a myocardial infarction (MI) and substitution of another analgesic such as acetaminophen. If NSAID therapy is unavoidable, the guidelines recommend the shortest duration possible.
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This single-center, double-blind, randomized, controlled crossover trial demonstrated that administration of 100% oxygen to stable patients with obesity hypoventilation syndrome leads to decreased minute ventilation, increasing dead-space to tidal volume ratio, and worsening hypercapnia.
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With the advent of new vaccines, the incidence of bacterial meningitis has declined, particularly in children, but the mortality rate has remained the same.
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Proton pump inhibitor use in clopidogrel-treated post-percutaneous coronary intervention patients was not associated with an increased risk of all-cause death, nonfatal myocardial infarction, repeat revascularization, or major adverse cardiovascular events.
