Critical Care
RSSArticles
-
IV Crystalloids: Is One Better Than the Other?
The decision of which fluid to use is highly variable and predominantly driven by local practice rather than patient or fluid characteristics.
-
Ceftazidime-avibactam — Formulary Considerations
Ceftazidime-avibactam is a new beta-lactam/beta-lactamase inhibitor combination approved for the treatment of complicated intra-abdominal infections in combination with metronidazole, and complicated urinary tract infections, including pyelonephritis in patients with limited alternative treatment options.
-
Idarucizumab Injection (Praxbind)
The FDA has approved the first reversal agent for a direct oral anticoagulant. Idarucizumab is a humanized monoclonal antibody fragment derived from an IgG1 isotype molecule. -
Optimal Beta-blocker Dose Post-MI
Beta-blocker therapy after acute myocardial infarction was retired as a hospital performance measure because its almost universal acceptance removed its discriminating value. However, it is well known that clinically used doses are significantly lower than those achieved in the randomized trials, establishing their mortality-reducing benefits.
-
Can We Safely Discharge Patients on the Weekend?
ABSTRACT & COMMENTARY: The link between weekend discharge and 30- and 90-day readmission rates.
-
Clinicians Are Skeptical of Early Warning Systems for Sepsis
While early warning systems for sepsis lead to clinical action, clinicians are skeptical and do not perceive them to be beneficial.
-
Bedside Ultrasound: Is It a Reliable Tool for Guiding Resuscitation in Patients with Undifferentiated Hypotension?
The use of bedside ultrasound for patients with undifferentiated hypotension in the emergency department substantially changed the plan of care and reduced physician diagnostic uncertainty.
-
Initial Choice of Fluid for Sepsis Resuscitation May Affect Mortality
The use of balanced salt solutions rather than isotonic saline or colloids may improve in-hospital mortality in patients admitted with septic shock.
-
Open Lung Biopsy in Critically Ill Patients
ABSTRACT & COMMENTARY: The procedure is associated with complication of persistent air leak and a significant hospital mortality of 54%.
-
Ultrasound for Trauma
Point-of-care ultrasound is a critical clinical tool that facilitates the early diagnosis of many life-threatening injuries. As with any test, clinicians need to fully appreciate indications and limitations of the diagnostic tool and integrate where advantageous to their practice.