Critical Care
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Can Procalcitonin Predict Need for ICU Admission in Community-acquired Pneumonia Patients?
Several studies have focused on the use of procalcitonin in diagnosing sepsis, as a prognostic marker in sepsis, and as a guide to antibiotic decisions in sepsis.
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Proportional Assist Ventilation and Lung Protection in Acute Respiratory Distress Syndrome: A Way Forward
A post-hoc analysis found that once patients were allowed to control their breathing pattern on high-level proportional assist ventilation, they continued to maintain an estimated driving pressure remarkably close to that measured during lung protective ventilation.
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How Good Is Passive Leg Raise at Predicting Fluid Responsiveness?
In a meta-analysis of 23 clinical trials, passive leg raise was shown to be an excellent predictor of fluid responsiveness.
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ICU Outcomes and Triage in Elderly Patients with Advanced Cancer
Here are the stats for those patients who are 80 years and older.
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Acetazolamide in Mechanically Ventilated Patients with COPD: Is There a Benefit?
Compared to placebo, the use of acetazolamide in mechanically ventilated patients with COPD does not significantly reduce the duration of mechanical ventilation. -
New Analysis of COGENT Data Supports Proton Pump Inhibitor Benefit with Low and High Aspirin Doses
A dedicated analysis of the COGENT trial involving coronary artery disease patients on dual antiplatelet therapy shows comparable risks of gastrointestinal and cardiovascular events between low- and high-dose aspirin, and similar benefits of prophylactic proton pump inhibitor therapy. -
Communication Facilitators Potentially Can Improve Care for the Sickest ICU Patients
Highly trained communication facilitators who counseled families and met with physicians and nurses were shown to decrease symptoms of depression in family members at six months and decreased ICU length of stay without affecting mortality. -
Rivaroxaban in the Real World
A large Phase IV registry study shows that rivaroxaban is associated with a very low incidence of major bleeding, death, or stroke. Also, adherence to therapy was much higher than observed in other studies with vitamin K antagonists. -
Delaying Intubation in Severe Alcohol Withdrawal
Delaying intubation until aspiration or cardiopulmonary decompensation did not affect mortality but increased the incidence of pneumonia and length of stay. -
Predicting the Success of Prone Positioning with Lung Ultrasound
Lung ultrasound may be useful in predicting which patients with acute respiratory distress syndrome would favorably respond to prone positioning.