Critical Care
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Vasopressin as a Single Vasopressor Agent in Patients with Septic Shock
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What Influences ICU Admission?
High ICU utilization hospitals were more likely to use invasive procedures and incur higher costs than low ICU hospitals with no difference in mortality.
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Airway Management in the Critically Ill: Challenges, Advances, and Controversies
Recent evidence and guidelines help inform best airway practice in the ICU, but challenges and controversies remain.
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Ticagrelor vs. Aspirin: Post-TIA and Stroke
The first 90 days after a transient ischemic attack or ischemic stroke is a high-risk period for recurrence of cardiovascular thrombotic events. Even with aspirin treatment, recurrences occur in as many as 10-15% of patients. -
Heart Failure with Recovered Ejection Fraction: A Distinct Phenotype
SYNOPSIS: Patients suffering from systolic heart failure who subsequently improve their ejection fraction experience a more favorable clinical course compared to those presenting with persistently reduced ejection fraction or heart failure with preserved ejection fraction.
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Noninvasive Ventilation Delivered Via Helmet May Decrease Intubation Rates
SYNOPSIS: In this single-center, randomized, clinical trial, among patients suffering from acute respiratory distress syndrome, the use of helmet noninvasive ventilation was associated with a reduction in intubation rates, ICU length of stay, and hospital and 90-day mortality.
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Influence of Sacubitril/Valsartan on 30-day Readmission After Heart Failure
SYNOPSIS: Compared with enalapril, treatment with sacubitril/valsartan is more effective in reducing 30-day readmissions for any cause following discharge from congestive heart failure hospitalization.
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Growing Threat of Pyelonephritis Caused by Antibiotic-resistant Escherichia coli
SYNOPSIS: In patients with acute pyelonephritis due Escherichia coli presenting to one of 10 emergency departments, the prevalence of fluoroquinolone resistance ranged from 6.3% to 19.9%, and the prevalence of extended-spectrum beta-lactamase production was 2.6% to 12.2%. Of those patients with resistant organisms, more than 50% received inactive empiric antibiotics.
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Safely Centralized Telemetry Off-site in a Multi-hospital System
SYNOPSIS: The hospitals in this study outsourced their cardiac telemetry to an off-site central monitoring center without an increase in adverse events.
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Spinal Cord Injury
The spinal cord, although well protected, can be injured in a variety of ways, including motor vehicle collisions and sporting events. The inability of the neurons to regenerate, and their sensitivity to anoxia and hypoperfusion, makes the timely diagnosis and treatment of spinal cord injury imperative to preserve as much function as possible. This article will cover the basic epidemiology, physiology, and treatments for spinal cord injury in an attempt to prepare the reader to manage these complex injuries.