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This multicenter, randomized, double-blind, placebo-controlled trial of hydrocortisone replacement in septic shock aimed to evaluate 28-day mortality in non-responders to corticotropin stimulation.
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Trauma surgeons at the Regional Medical Center at Memphis carried out a randomized clinical trial comparing a continuous ethanol infusion with a protocol of scheduled diazepam administration for the prevention and control of severe alcohol withdrawal syndrome (AWS) among patients admitted to their ICU following trauma.
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It is now well established that ventilating patients with acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) using a strategy that limits alveolar distending volume and end-inspiratory static airway pressure results in improved survival, as compared to larger-volume, higher-pressure ventilation.
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This multicenter randomized trialnicknamed the VISEP studyused a two-by-two factorial design to test two independent treatments in severe sepsis patients.
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In this issue: Does erythropoietin worsen cancer death rates? Most hypothyroid patients can be replaced with levothyroxine alone without additional T3. Does aggressive control in type 2 diabetes save lives?
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Myocarditis may have a wide variety of etiologies and presentations and the clinician must have an awareness of this disease process to adequately screen patients. Although viral infections are the most common etiology, noninfectious etiologies also may occur. This article provides a review of the diverse presentation, assessment, and management of a child with myocarditis.
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Physicians need to understand the pathophysiology, preventative
strategies, and acute management of patients with altitude sickness.
This article presents an overview of the spectrum of altitude illness,
diagnosis, and current management strategies, as well as preventative
strategies.
