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With the increasing skill of our NICUs in saving extremely premature babies and the capability of rescuing children with acute illnesses and injuries in our PICUs, children with special healthcare needs are being discharged from tertiary centers and returning to their home communities.
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In this Issue: Pioglitazone and heart disease; ARBs manufacturers spend
millions to show the non-inferiority of their products compared to less
expensive, generic ACE inhibitors; some athletes turn to growth hormone
because it is difficult to detect; FDA Actions
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For 2 years beginning in February, 2005, every patient admitted to the Royal Infirmary of Edinburgh with community-acquired pneumonia (CAP) had blood levels of C-reactive protein (CRP) measured at the time of admission and (if still in the hospital) 4 days later. A standardized set of clinical and laboratory data was also acquired for each patient, per hospital routine.
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Starting 4 months after publication of the ARDS Network's landmark study showing improved outcomes in patients with acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS) when low-tidal-volume, lung-protective ventilation (LPV) was used, investigators at the University of Pennsylvania prospectively identified 88 patients who met the accepted American-European Consensus Conference definition of ALI-ARDS.
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While only a minority of patients with asthma exacerbations require ICU admission, these patients are challenging to manage because they typically have already failed treatment in the outpatient and emergency department (ED) settings.
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Patients experience headache more than any other form of pain. Headaches account for more than 10 million physician visits annually, including 0.5-2.7% of emergency department (ED) visits.
