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Family members who received a diary written during their family members ICU admission had lower levels of symptoms related to post-traumatic stress disorder.
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In the first report (Newland et al), a quasi-experimental study with a control group (also known as a nonrandomized, postintervention design) was performed from 20042010 to determine the impact of an antimicrobial stewardship program (ASP) implemented in March 2008 in a tertiary care childrens hospital that was based on prospective-audit-with-feedback. The control group included 25 childrens hospitals.
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Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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In this single-center, prospective study, median duration of antibiotics for community-acquired pneumonia (CAP) decreased from 10 to 7 days with an antibiotic stewardship program that included education and prospective feedback to the managing team.
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The use of non-steroidal anti-inflammatory drugs (NSAIDs) early after myocardial infarction (MI) has been shown to increase the risk of death or recurrent MI, but little is known about the long-term risks. Thus, this group from Denmark evaluated their national database and identified more than 99,000 patients who survived 30 days after discharge following their first MI.
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This study reports data from the International Collaboration on Endocarditis-Prospective Cohort Study (ICE-PCS) on the clinical characteristics of infective endocarditis related to pacemakers and ICDs. ICE-PCS collected data on 3284 patients with endocarditis from 64 centers in 28 countries in a central database.
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Linezolid was non-inferior to vancomycin in patients with nosocomially acquired MRSA pneumonia. Although mortality was similar among linezolid- and vancomycin-treated patients, several outcomes (such as clinical cure and microbiological cure) favored linezolid.
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Institution of a formal audit and feedback program resulted in a decrease in use of broad-spectrum antibiotics and a 31% reduction in cases of Clostridium difficile infection.