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Salvage therapy of invasive aspergillosis with posaconazole was associated with a 42% response rate, compared to only 26% in an external control group.
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Using the metyrapone test as a gold standard, the authors confirmed that a resting serum cortisol level < 10 micrograms/dL, or an increase of < 9 micrograms/dL after cosyntropin stimulation, accurately diagnoses adrenal insufficiency in ICU patients with severe sepsis or septic shock.
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In a study involving 108 ICUs in Michigan, an evidence-based intervention led to a 66% reduction in catheter-related bloodstream infections that was sustained over an 18-month period.
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Searching Google yielded a correct diagnosis in greater than half of cases.
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A multicenter, observational study retrospectively compared 59 individuals with acute or early HIV infection who elected to receive antiretroviral (ARV) therapy for 12 weeks to 337 patients who declined treatment.
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Part II of this series discusses the use of anticoagulants in the emergency department (ED) and some of the complications seen with their use. As our society ages, more and more patients are on chronic anticoagulants.
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It is very common for adolescent females to present with menstrual irregularities and differentiating normal variations from life-threatening problems is critical to the emergency department physician.