Critical Care General
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Ketamine vs. Etomidate for Emergency Intubation
In a single-center, open label study, ketamine for emergency intubation compared to etomidate was associated with lower seven-day mortality, although 28-day mortality was similar.
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Awake Prone Positioning for COVID-19-Related Acute Hypoxemic Respiratory Failure
This special feature summarizes the literature associated with awake prone positioning (APP), describes known factors related to successful APP, and highlights current recommendations regarding APP in the setting of COVID-19.
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Midline Catheters May Be a Safer Option than Peripherally Inserted Central Catheters
Whenever possible, use of midline catheters over peripherally inserted central catheters could be safer for patients.
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‘Code Critical’ Process Speeds Care to Critically Ill Patients Who Present to ED
In 2016, a suburban California emergency department began working on a new alert process designed to ensure medical patients not covered by alerts already in place would receive the same type of rapid, timely response that other alerts trigger. The resulting approach, dubbed “code critical,” has proven successful at accelerating care to a broad category of critically ill patients.
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Peramivir: A Newly Approved Antiviral for Treatment of Influenza
Peramivir (Rapivab™) was recently approved by the FDA in December 2014 for treatment of acute uncomplicated influenza within two days of symptom onset. This newly approved antiviral is a neuraminidase inhibitor (NI) similar to oseltamivir and zanamivir but the first to be approved in an injectable formulation.1 Peramivir has been licensed in Japan (as Rapiacta) and South Korea (as PeramiFlu) since 2010. In addition, it has been used in the United States on an emergency basis during the 2009 H1N1 flu pandemic.
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Multicenter Quality Improvement Project Resulted in a 23% Reduction in Medical Errors
SYNOPSIS: Implementation of a quality improvement project focused on handoffs reduced medical errors by 23% and preventable adverse events by 30%.
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Benefits of NIV in COPD Supported in Routine Clinical Practice
SYNOPSIS: In a large cohort study, patients with chronic obstructive pulmonary disease managed with noninvasive ventilation had lower inpatient mortality, shorter length of stay, and lower costs compared to those managed with invasive ventilation.
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Transient Ischemic Attacks: A Missed Opportunity
SYNOPSIS: Patients with transient ischemic attacks were not given evidence-based secondary prevention for stroke at discharge from the hospital as often compared to patients with stroke, thus creating a missed opportunity to decrease the incidence of future stroke and cardiovascular disease.
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Does Your Patient Have a Central Venous Catheter?
Central venous catheters (CVCs) are essential to providing optimal care to many hospitalized patients.
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Pharmacology Watch: HPV Vaccine Now Recommended for Males
In this issue: New recommendations for HPV vaccine; guidelines for treatment of essential tremor; updates on smoking cessation drugs; and FDA actions.