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This 3-year cohort surveillance study of all adult patients admitted to ICUs in one region found that they were common (developing in 6.5% of patients, or 9.6 UTIs per 1000 ICU days) but did not contribute independently to mortality.
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In this in-depth examination of 111 patients at a center in the original ARDS Net low-tidal-volume study, patients managed with 6 mL/kg or less did not require more sedation during the first 48 hours than those managed with tidal volumes of 12 mL/kg.
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This prospective, randomized trial evaluated the role of early percutaneous tracheostomy in critically ill adults projected to require more than 14 days of mechanical ventilation. They found significant reductions in ICU length of stay, the incidence of ventilator-associated pneumonia, and mortality.
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This cost-effectiveness analysis based on available published data suggests that the routine use of maximum sterile barriers for central venous line insertion would reduce the incidence of line-related infections and save both money and lives.
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Promising New Weight Loss Drug?; Treating Shift-Work Disorder; Another Flu Vaccine Shortage?; FDA Actions
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In this multicenter clinical trial of patients with severe community-acquired pneumonia, a 7-day course of low-dose hydrocortisone infusion was associated with decreased signs of inflammation and significant reductions in duration of mechanical ventilation, hospital length of stay, and in-hospital mortality.
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This single-center, prospective, observational study of resuscitation for in-hospital cardiac arrest reveals that the performance of cardiopulmonary resuscitation is inconsistent with current guidelines.
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Neuropsychiatric Symptoms of Dementia, FDA Actions.