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The ICU is commonly viewed as a stressful environment. While common, stress responses are likely to vary over time, between individuals, and as a result of the context in which they occur.
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Colonization of the respiratory tract and other sites with Candida species is common in ICU patients but it is unclear how often these species cause pneumonia that warrants antifungal therapy.
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Along with yearly vaccination, the U.S. Centers for Disease Control and Prevention (CDC) recommend the use of personal protective equipment (PPE) by health care workers (HCWs) to prevent influenza infection in the ICU.
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In this issue: Aspirin dose and cardioprotection; uncovering modafinil's abuse potential; proton-pump inhibitors and clopidogrel; FDA actions.
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In the application of non-invasive ventilation (NIV) in the management of patients with acute respiratory failure, Fraticelli and colleagues at Henri Mondor Hospital in Créteil, France, sought to determine the clinical effects of using interfaces with varying dead space and other features.
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Patients with acute coronary syndrome present one of the most common admission diagnoses in the intensive care unit. For non-cardiology intensivists, the ever-evolving treatment algorithms present a challenging body of literature on which to remain current.
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Editor's Note: The alpha2-receptor agonist dexmedetomidine (Precedex®), introduced for perioperative and procedural sedation and other short-term applications, is approved by the FDA for use in the ICU, although the package insert emphasizes that this approved use is for not more than 24 hours.
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While ICU clinicians understand that prognostic uncertainty is a normal part of critical care, it is unclear if surrogates hold similar views. In this study, Evans et al conducted semi-structured face-to-face interviews with 179 surrogates who had an adult patient in the ICU.
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In this issue: Individualization of therapy with pharmacogenetics; the rate vs rhythm debate; the FDA's Risk Evaluation and Mitigation Strategy; FDA actions.