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This paper reports on a comprehensive follow-up of patients with severe airway obstruction who were admitted to 92 ICUs or to 3 high-dependency respiratory units in the United Kingdom during 2002 and 2003.
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In this issue: Comparing blood pressure medications, determining optimal length of androgen-deprivation therapy, red yeast rice for LDL reduction, and FDA Actions.
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Early goal-directed therapy (EGDT) has been shown to reduce hospital mortality from severe sepsis and septic shock. Puskarich et al hypothesized that long-term outcome would also be improved.
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In this issue: Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
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Prone positioning has been advocated as a management strategy for patients with acute respiratory distress syndrome (ARDS), but despite evidence of improved oxygenation with the technique, numerous studies have yet to establish a mortality benefit from the practice.
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Prior studies have demonstrated that delayed transfer of critically ill patients from the emergency department (ED) to the ICU (> 6 hours) prolongs ICU and hospital stay.
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Every intensivist recognizes that families play a prominent role in ICU decision making.
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In addition to their cholesterol-lowering properties, hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors, commonly referred to as statins, have been shown to modify inflammatory and immunologic pathways.
