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Do Antidepressants Increase Risk of Suicide?; Can Viagra Improve Heart Function?; A Dramatic Increase of Clostridium difficile; FDA Actions
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Propylene glycol is used as the carrier vehicle for a number of drugs including lorazepam and diazepam. It may cause metabolic abnormalities such as anion gap metabolic (usually lactic) acidosis and hyperosmolality.
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In this study from the University of Liverpool, Duffy and associates sought to determine whether the addition of intravenous aminophylline produced clinically important improvements in the rates of symptomatic recovery or increases in pulmonary function, and whether it shortened hospital stay, in comparison with standard therapy without aminophylline, among patients with COPD who were admitted with an exacerbation.
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Infection control practices often target clinician behaviors, eg, improving adherence to hand washing hygiene and other infection control practices.
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A 53-year-old woman with a history of splenectomy 15 years ago for idiopathic thrombocytopenic purpura and no chronic medical problems awoke with headache, myalgias, and fever. She was seen at her local urgent care that evening where she had a temperature of 102°F with mild tachycardia but otherwise normal vital signs.
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A 58-year-old woman presented with 3 days of dyspnea and was shown by CT scan to have pulmonary thromboemboli. She was anticoagulated with low-molecular-weight heparin and was stable for 2 days, but then developed acute respiratory failure, was intubated, and transferred to the ICU.
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Alternative Therapy for Depression?; FDA Actions
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When study data were used to perform a formal analysis of costs associated with use of erythropoietin, the total cost to avoid one transfusion-related adverse event was $4.7 million.
