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Severe sepsis with organ failure has one of the highest mortality rates of any diagnosis commonly treated in the Intensive Care Unit. Recent clinical trials have provided some positive results with reductions in overall mortality from sepsis.
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Despite favorable reviews, limited evidence supports the benefit of high fidelity human simulation (HFHS) in preference to more traditional forms of health care provider education.
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Kalhan and colleagues at the hospital of the University of Pennsylvania (a participating ARDSNet investigation site) performed a prospective observational cohort study of patients with acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS) managed in their ICUs during a 22-month period beginning after publication of the initial ARDSNet study.
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Using a website-based international registry of patients with catastrophic antiphospholipid syndrome (CAPS), Bucciarelli et al sought to determine how often ARDS occurred as a complication.
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Some studies have shown that breathing through an endotracheal tube imposes a small but measurable excess respiratory workload.
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Treatment of Benign Prostatic Hyperplasia; Treatment of Osteoarthritis of the Knee; Refractory Asthma and TNFConnection?; FDA Actions
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Nosocomial infections are unfortunately common in intensive care units all across the United States. Although a wide variety of guidelines and treatment options exist for common types of nosocomial infections, such as catheter-related bloodstream infections or the ventilator-associated pneumonia, much less importance is given in critical care to Clostridium difficile infections.
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In this study from the University of Liverpool, Duffy and associates sought to determine whether the addition of intravenous aminophylline produced clinically important improvements in the rates of symptomatic recovery or increases in pulmonary function, and whether it shortened hospital stay, in comparison with standard therapy without aminophylline, among patients with COPD who were admitted with an exacerbation.