Critical Care Alert
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Are Nighttime Extubations in the ICU Safe?
Compared to daytime extubations, ICU patients who undergo planned extubation at night do not experience higher likelihood of reintubation, increased length of stay, or increased mortality.
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Head-elevated Positioning May Decrease Complications of Emergent Tracheal Intubation
In emergent intubations, a position in which the angle of the back was > 30 degrees above the horizontal (head-elevated) position was associated with fewer complications than intubations performed in the supine position, but the study has several limitations.
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ICU Capacity Strain
ICUs are faced with the challenge of continuing care delivery under conditions of increasing strain that's tough to get a handle on.
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Apneic Oxygenation During Intubation for Respiratory Failure
Use of apneic oxygenation with a high-flow nasal cannula during endotracheal intubation for acute respiratory failure is no better at preventing arterial oxygen desaturation than usual care using pre-oxygenation.
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Does Acetaminophen Help Febrile Patients with Infection?
Scheduled intravenous acetaminophen lowers temperature but does not affect ICU-free days, mortality, length of stay, or adverse events in patients with sepsis.
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What is the Best Rate Control Agent for Patients with Sepsis and Atrial Fibrillation?
Beta-blockers may be associated with better outcomes in patients with sepsis and atrial fibrillation.
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Dyspnea and Asynchrony During Mechanical Ventilation
Breathing is the primal sensation of postnatal life, the disturbance of which produces the most profound sense of dread.
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Does the Use of Saline vs Buffered Crystalloid Reduce Risk of Acute Kidney Injury in ICU?
The use of a buffered crystalloid compared with saline did not reduce the risk of acute kidney injury in patients receiving crystalloid fluid therapy in the ICU.
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Effects of a Rapid Response System Driven by Real-time Automated Clinical Alerts on Hospital Mortality and Length of Stay
The addition of an automated real-time clinical deterioration alert system to a rapid response system had marginal effects.
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New Insights Into Alveolar Mechanics and Gas Exchange in Experimental Acute Respiratory Distress Syndrome
Experimental acute respiratory distress syndrome was induced in mice to study local alveolar gas dynamics using advanced microimaging techniques. Heretofore unrecognized disturbances in alveolar ventilation will alter our understanding of alveolar mechanics and gas exchange dysfunction as well as promote the use of recruitment maneuvers.