Critical Care Alert
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Antibiotic Treatment in Community-acquired Pneumonia
In patients with newly diagnosed community-acquired pneumonia, basing the duration of antibiotic treatment on clinical stability criteria led to a significant reduction in duration of antibiotic treatment without an increased risk of adverse outcomes.
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Is There an Optimal Blood Pressure Target in Patients Presenting with Intracerebral Hemorrhage?
Recently, two large randomized, controlled trials compared intensive blood pressure control with permissive hypertension in the setting of acute intracerebral hemorrhage. The authors of the two trials reached seemingly differing conclusions, leading to confusion on how to best manage patients.
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Categorizing Acute Respiratory Distress Syndrome as Direct vs. Indirect Injury
This retrospective observational study compared patients with acute respiratory distress syndrome classified as presenting with direct vs. indirect lung injury and found distinct differences in traditional predictors of hospital mortality between these subgroups.
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Reducing Stress and Anxiety in Mechanically Ventilated, Critically Ill Patients: Does Chaplain-assisted Spiritual Care Play a Role?
In mechanically ventilated, critically ill patients without delirium or dementia, chaplain-led, picture-guided spiritual care is feasible and shows the potential for reducing anxiety and stress during and after an ICU admission.
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A Prospective, Randomized Comparison of Video and Direct Laryngoscopy
In the largest prospective, randomized trial to date, use of video laryngoscopy improved glottic visualization but did not increase procedural success or decrease complications compared to direct laryngoscopy in medical ICU patients.
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Early Initiation of Continuous Renal Replacement Therapy May Reduce Mortality in Patients Who Require Dialysis
Initiation of continuous renal replacement therapy for patients with Kidney Disease: Improving Global Outcomes stage 2 renal failure reduced 90-day all-cause mortality.
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High-flow Nasal Cannula vs. Noninvasive Ventilation in Postextubation Failure: Does It Matter?
In this multicenter, randomized, clinical trial of critically ill adults at high risk for reintubation, high-flow conditioned oxygen therapy was not inferior to noninvasive mechanical ventilation with regard to preventing reintubation and postextubation respiratory failure within 72 hours of extubation.
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Should We Use Non-invasive Ventilation to Treat Acute Respiratory Distress Syndrome?
Managing acute respiratory distress syndrome (ARDS) with non-invasive ventilation was associated with increased failure as the severity of ARDS increased.
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Rehabilitation in the ICU: More Questions Than Answers
In patients with acute respiratory failure, standardized rehabilitation therapy consisting of passive range of motion, physical therapy, and progressive resistance exercise did not decrease hospital length of stay compared to usual care.
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A New Paradigm in the Management of Massive and Submassive Pulmonary Embolism
A multidisciplinary pulmonary embolism (PE) response team is a sustainable option to improve care for severe PE.