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In patients with acute lung injury or ARDS, the addition of higher PEEP levels to the strategy of a low tidal volume does not improve clinical outcomes.
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There currently exists much evidence to direct the application of Noninvasive Positive Pressure Ventilation (NPPV). NPPV for the treatment of patients with acute respiratory failure has generated several meta-analyses and systematic reviews,1-4 including a recent one by Dean R. Hess PhD, RRT.
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In patients with ALI/ARDS from pulmonary and extrapulmonary causes, receiving mechanical ventilation with low tidal volumes and high PEEP, short-term effects of recruitment maneuvers as conducted in this study are variable.
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Steroids Not Linked to Risk of Fractures; ADT Puts Men at Risk for Osteoporosis; Study Shows Valsartan May Improve Sexual Function in Postmenopausal Women; New Direct-to-Consumer Pharma Advertising Rules Considered; FDA Actions
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A consensus group making recommendations on the use of restraining therapies in the ICU emphasizes the inadequacy of the evidence base in this area and calls for studies to generate better data.
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This single-center study reveals that, compared to continuous sedation, daily sedative interruption is not associated with adverse psychological effects after 6-21 months.
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Adult patients presenting with acute asthma without significant respiratory acidosis who were given 100% oxygen to breathe had slight increases in arterial PCO2 and slight decreases in arterial pH and peak expiratory flow, as compared with patients who received only 28% oxygen.
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In late-onset VAP, survival improved and costs decreased using initial coverage with 3 antibiotics. Mini-BAL did not improve survival but decreased costs and antibiotic usage.
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