Critical Care Alert
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Special Feature: Critical Care Management of the Jehovah’s Witness Patient
Few clinical situations place intensive care practitioners in a more uncomfortable position than does treating patients of the Jehovahs Witness faith. The faith-based refusal of autogenous or allogenic blood transfusions conflicts with the typical life-saving intent implicit in the critical care environment. However, it is our obligation to have a basic level of understanding of the set of beliefs that leads to the choice to refuse this specific set of life-saving therapies, while accepting other aspects of modern medical care. -
Pharmacology Watch: Estrogen Found to Not Affect Heart Disease, Breast Cancer
Antibiotics Associated With Cancer Risk; Topiramate Effective Against Migraine; Statin Therapy For Heart Failure; FDA Actions. -
Clinical Briefs in Primary Care
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Should Patients with End-Stage Liver Disease be Intubated?
Mortality among patients with advanced cirrhosis who required intubation and mechanical ventilation was related more to the derangement of liver function than to the severity of critical illness as assessed by APACHE II or SAPS. -
Pharmacology Watch: Hypertension: Therapy vs Calcium Channel Antagonists
GEMINI Trial; CAMELOT Trial; INVEST Trial; The Dangers of Vitamin E; FDA Actions. -
Effect of Kinetic Therapy on Pulmonary Complications
The primary objective of this study was to determine whether patients receiving mechanical ventilation who tolerate kinetic therapy have better pulmonary function than patients treated with standard turning. A secondary objective was to assess the cost-effectiveness of kinetic therapy. -
Special Feature: The Highly Reliable ICU
Adverse events and hospital deaths are common, and when these are combined, a large proportion of deaths are deemed preventable. Are there organizational approaches we can adopt in the ICU that will create a safer place? -
Clinical Briefs in Primary Care supplement
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Pharmacology Watch: New Clinical Guidelines on Cholesterol Management
Hypothyroidism and Pregnancy; Anti-Depressants and the Risk of Suicide; FDA Actions; Brief Notes. -
Clinical Briefs in Primary Care supplement