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Antibiotics Associated With Cancer Risk; Topiramate Effective Against Migraine; Statin Therapy For Heart Failure; FDA Actions.
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Few clinical situations place intensive care practitioners in a more uncomfortable position than does treating patients of the Jehovahs Witness faith. The faith-based refusal of autogenous or allogenic blood transfusions conflicts with the typical life-saving intent implicit in the critical care environment. However, it is our obligation to have a basic level of understanding of the set of beliefs that leads to the choice to refuse this specific set of life-saving therapies, while accepting other aspects of modern medical care.
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Adverse events and hospital deaths are common, and when these are combined, a large proportion of deaths are deemed preventable. Are there organizational approaches we can adopt in the ICU that will create a safer place?
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The primary objective of this study was to determine whether patients receiving mechanical ventilation who tolerate kinetic therapy have better pulmonary function than patients treated with standard turning. A secondary objective was to assess the cost-effectiveness of kinetic therapy.
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GEMINI Trial; CAMELOT Trial; INVEST Trial; The Dangers of Vitamin E; FDA Actions.
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Mortality among patients with advanced cirrhosis who required intubation and mechanical ventilation was related more to the derangement of liver function than to the severity of critical illness as assessed by APACHE II or SAPS.
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There currently exists much evidence to direct the application of Noninvasive Positive Pressure Ventilation (NPPV). NPPV for the treatment of patients with acute respiratory failure has generated several meta-analyses and systematic reviews,1-4 including a recent one by Dean R. Hess PhD, RRT.
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In patients with acute lung injury or ARDS, the addition of higher PEEP levels to the strategy of a low tidal volume does not improve clinical outcomes.