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In this issue: Examining the three arms of the ACCORD trial; and FDA Actions: clopidogrel, dexlansoprazole, and tamsulosin.
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Endotracheal intubation is a procedure fraught with multiple, potentially life-threatening complications.
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Kim and associates conducted a population-based, retrospective cohort study of medical patients admitted to acute care hospitals throughout the state of Pennsylvania between July 2004 and June 2006.
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The authors conducted a single-center, randomized, non-blinded study of critically ill patients who were expected to need mechanical ventilation > 24 hours.
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Passive leg raising (PLR), a rapidly reversible maneuver that simulates rapid volume expansion by putting several hundred milliliters of fluid back into the circulation, has been shown to predict fluid responsiveness in mechanically ventilated patients.
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With increased emphasis on evidence-based medicine during the last dozen years has come the implicit assumption that the availability of more and better evidence on how disease should be diagnosed and managed will lead to better patient care.
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Passive leg raising (PLR), a rapidly reversible maneuver that simulates rapid volume expansion by putting several hundred milliliters of fluid back into the circulation, has been shown to predict fluid responsiveness in mechanically ventilated patients.
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In this issue: FDA is reviewing safety of TZDs; SSRI use with tamoxifen; Metformin smells like fish; FDA Actions.
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