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Optimal treatment for carcinoma of unknown primary has not been established. In a multicenter, randomized Phase II trial, 66 patients were treated with cisplatin, gemcitabine and either paclitaxel or vinorelbine.
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Immediate breast reconstruction after mastectomy has intuitive appeal, but concern has been raised that such an approach hinders postmastectomy radiotherapy.
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Breast cancer patients who received either high-dose, standard-dose or no chemotherapy were studied prospectively, utilizing a comprehensive battery of neuropsych tests.
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An increasing number of active therapies have become available for multiple myeloma in addition to high dose chemotherapy followed by autologous transplant (ASCT).
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Patients with coronary artery disease who have received intra-coronary, drug-eluding stents (DES) may benefit from longer courses of clopidogrel than is currently standard.
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Beta-Blockers Therapy for the Treatment of Hypertension; Treatments for Acute Migraine; Statin Therapy for ACS Patients; The Correct Dosing for Onychomycosis; FDA Actions
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Breast cancer in young women is uncommon, but when it does occur, it is thought to be very aggressive. In this large series of young (< 35 years old) patients from a single institution seen over a 13-year period, high tumor grade, hormone receptor negativity, and family history of ovarian cancer turned out to be significant negative prognostic indicators.
