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Clinical

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Articles

  • Pharmacology Watch: Critical Drug Shortages Are on the Rise

    In this issue: Drug shortages; metformin and cancer prevention; migraine prevention guidelines; and FDA actions.
  • IUDs in Nulliparous Women

    To investigate the attitudes and practices of health care providers toward intrauterine device (IUD) use in nulliparous women, the authors performed a national survey of both office-based physicians and Title X health care providers from December 2009 to March 2010.
  • Shoulder Dystocia

    For years, clinicians have been trying to find ways to predict shoulder dystocia (SD), a complication that can have serious consequences for some infants and, on occasion, for the providers who delivered these babies.
  • Paracervical Block for Pain Control

    The authors performed a randomized, single-blind trial of the effects of a paracervical block (PCB) or sham block on pain with cervical dilation and aspiration during first trimester abortion. Enrollment of subjects was stratified by gestational age (early: < 8 weeks, n = 60; late: 8-10 6/7 weeks, n = 60).
  • Clinical Briefs in Primary Care

    Donepezil and Memantine for Moderate-Severe Alzheimer's Disease; Treating Hyperhidrosis with Systemic Therapy; A New Intervention for Actinic Keratoses: Ingenol Mebutate Gel; Colon Cancer Screening: Getting the Right Test Done; Can Male Pattern Baldness Predict BPH?
  • ECG Review: Adenosine for a Wide Tachycardia?

    Scenario: The 12-lead ECG shown above was obtained from a previously healthy 30-year-old man who presented to the emergency department with new-onset palpitations. No prior ECG was available for comparison. The patient was alert and hemodynamically stable at the time this tracing was recorded. What is the rhythm? Is this rhythm likely to respond to adenosine?
  • Pharmacology Watch: FDA Approves First New Anti-Obesity Drug in Years

    Lorcaserin for weight loss; statins and fatigue; treatment-resistant gonorrhea; hydrocodone classification changes; USPSTF recommendations; and FDA actions.
  • Risk of Sudden Cardiac Death with Azithromycin

    In this paper, the authors performed a pharmacoepidemiologic study on the relationship between azithromycin, a frequently used broad-spectrum macrolide antibiotic, and cardiovascular death. The authors analyzed data from the Tennessee Medicaid program.
  • High-Flow Nasal Cannula Oxygen Therapy in Acute Respiratory Failure: What Do We Know?

    Limited data on the use of high-flow nasal cannula oxygen therapy suggests it is associated with improvement in physiologic parameters.
  • Medical Emergency Team Calls in the Radiology Department

    This study of potentially life-threatening changes in patient condition during trips to the radiology department of a large academic medical center found that such events occurred about once a week, involved both ward and ICU patients who had comorbidities and high overall mortality, and were often unanticipated by vital sign changes or other recognized warnings.