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Patients who present with acute myocardial infarction (MI) complicated by cardiogenic shock represent a group at high risk for early mortality. Current guidelines recommend the use of intra-aortic balloon pump (IABP) for these patients, but there are few randomized, controlled trial data to support this.
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Two men presented to a hospital in northwestern Missouri in June 2009 with fever, fatigue, diarrhea, thrombocytopenia and leukopenia. Both had a history of frequent recent tick bites. A novel phlebovirus was isolated in cell culture from patient blood. Electron microscopy revealed virus particles consistent with Bunyaviridae. Sequencing identified the viruses as novel members of the phlebovirus genus.
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Small subcortical brain infarcts, known as lacunar strokes, account for about 25% of all ischemic strokes.
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A historical cohort study from San Francisco General Hospital evaluated patients ≥18 years old that were hospitalized and received at least one dose of ceftriaxone. In a multivariable analysis, for every day a patient also received doxycycline the rate of Clostridium difficile infection was 27% lower than for those who did not receive doxycycline (hazard ratio, 0.73%; 95% confidence interval, 0.56-0.96).
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Patients who received treatment for depression within a year were identified in a Japanese database of more than 323,000 patients. The investigators asked 2354 patients to complete a questionnaire on depression with a specific focus on patient-physician relationships.
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Every so often, one runs across a paper that is somewhat offbeat, but could have some beneficial clinical implications. One such article appeared recently in the British Journal of Obstetrics and Gynecology that dealt with a way to possibly counter the fetal effects of maternal hyperthermia and even protect the brains of fetuses/infants against potential hypoxic insult during labor.
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Through the contraceptive choice project, the authors performed a prospective cohort study in which 9256 women living in the region surrounding St. Louis, Missouri, received a reversible contraceptive method of their choice for up to 3 years at no cost.
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