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Professor of Medicine, Chief of Clinical Cardiology, University of California, San Francisco
Synopsis: The beneficial effects of drug-eluting stents on coronary artery lumen enhancement are preserved for 4 years after implantation.
Source: Sousa JE, et al. Four-Year Angiographic and Intravascular Ultrasound Follow-Up of Patients Treated with Sirolimus-Eluting Stents. Circulation. 2005:111:2326-29.
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By Michael H. Crawford, MD
Synopsis: Higher BNP levels predict worse outcomes under medical management and may be useful for decisions regarding surgery.
Source: Detaint D, et al. B-Type Natriuretic Peptide in Organic Mitral Regurgitation. Circulation. 2005;111:2391-2397.
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By Jonathan Abrams, MD
Professor of Medicine, Division of Cardiology, University of New Mexico, Albuquerque
Dr. Abrams serves on the speakers bureau for Merck, Pfizer, and Parke-Davis.
Synopsis: In order to reduce CVD mortality, more active management and prevention of diabetes is needed.
Source: Hu G, et al. The Gender-Specific Impact of Diabetes and Myocardial Infarction at Baseline and During Follow-Up on Mortality From All Causes and Coronary Heart Disease. J Am Coll Cardiol. 2005;45:1413-1418.
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By John P. DiMarco, MD, PhD
Synopsis: Data are consistent with the concept that autonomic imbalance predisposes persons to life-threatening arrhythmias.
Source: Jouven X, et.al. Heart-Rate Profile During Exercise as a Predictor of Sudden Death. N Engl J Med. 2005;352:1951-1958.
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By Michael H. Crawford, MD
Synopsis: Damage to the tricuspid valve caused by electrophysiologic device leads may be a cause of predominant right heart failure due to severe TR and may not be recognized on routine echocardiography.
Source: Lin G, et al. Severe Symptomatic Tricuspid Valve Regurgitation Due to Permanent Pacemaker or Implantable Cardioverter-Defibrillator Leads. J Am Coll Cardiol. 2005;
45:1672-1675.
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Acute lower respiratory tract infection (bronchitis) is the most common complaint bringing patients to the doctor in England, where it is estimated that 75% of these patients receive an antibiotic at the first visit.
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By Claire Henchcliffe, MD
Synopsis: Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinsons disease after some 6-12 months of treatment.
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By Claire Henchcliffe, MD
Assistant Professor of the Department of Neurology at Weill Medical College, Cornell University
Dr. Henchcliffe is on the speakers bureau for GlaxoSmithKline, Teva/Eisai, and Boehringer Ingelheim.
Synopsis: Depression and anxiety in Parkinsons disease might be associated with a specific loss of dopamine and noradrenaline innervation in the limbic system.
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By M. Flint Beal, MD
Professor and Chairman of the Department of Neurology at Cornell Medical College
Dr. Beal reports no consultant, stockholder, speakers bureau, research, or other relationships related to this field of study.