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Evidence of Clinical Efficacy of Bebtelovimab in COVID-19
In a retrospective study, bebtelovimab demonstrated efficacy similar to Paxlovid in high-risk outpatients with recent onset of COVID-19 who reported mild to moderate symptoms.
Spironolactone May Help Treat Chronic Alcoholism
Both animal and human studies suggest spironolactone might be a new agent for helping patients with alcohol use disorder cut their intake.
Does Shoulder Simulation Training Decrease the Incidence of Brachial Plexus Injury?
This study demonstrated that improved team and individual performance can result from systematic simulation-based shoulder dystocia training, which can considerably lower the incidence of permanent brachial plexus injuries.
Ultrasound to Detect Endometrial Cancer and Endometrial Intraepithelial Neoplasia in Patients Without Abnormal Bleeding
In women without abnormal uterine bleeding undergoing transvaginal ultrasound, endometrial intraepithelial neoplasia or endometrial cancer was associated with a thicker endometrium, heterogenous echotexture, more frequent endometrial cysts, and increased vascularity.
Labiaplasty in the United States
In this descriptive study, the rates of labiaplasty from 2016-2019 in the United States ranged from 3,046 to 4,315 per year and were highest among women aged 18 to 35 years.
The Harms of Urine Drug Screening for Isolated Marijuana Use on Labor and Delivery Units
Isolated marijuana use, when used as an indication for urine drug screening during the labor and delivery period, poorly predicts concomitant use of other nonprescribed substances. However, use of the screening brings real risk of inequitable harm.
Periodontal Disease as an Independent Risk Factor for Cardiovascular Disease
Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.
Is Illicit Substance Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.
Another Marker of Severe Mitral Regurgitation
A small retrospective study showed Doppler echocardiography-derived left ventricular ejection time is an independent predictor of adverse outcomes in patients with moderate or worse mitral valve regurgitation.
The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.