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The FDA has recently approved daptomycin for use in skin and skin-structure infections, but this antibiotic failed the test of non-inferiority in a trial of severe community-acquired pneumonia.
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Saccharomyces boulardii (recently recognized as a strain of S. cerevisiae rather than a distinct species) is widely used as a probiotic for the treatment of diarrhea and for the prevention and treatment of C. difficile-associated colitis.
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Musher and colleagues followed 207 patients with C. difficile colitis treated with appropriate (at least 1.5 gm/day) doses of metronidazole for at least 7 days. All patients had a positive stool ELISA assay for C. difficile toxin.
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Two definite (culture-confirmed), and one probable, cases of K. kingae invasive disease were reported in Minnesota in October 2003, among children attending the same toddler classroom of a childcare center.
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Promising New Weight Loss Drug?; Treating Shift-Work Disorder; Another Flu Vaccine Shortage?; FDA Actions
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Over the past decade, there has been growing concern about the magnitude of antimicrobial resistance, particularly among gram-positive organisms such as penicillin-resistant Streptococcus pneumoniae, methicillin-resistant staphylococci, and vancomycin-resistant enterococci.
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Consider these facts: Women are the fastest-growing group in the United States with newly diagnosed HIV, and last year, an estimated 6,000-7,000 women with HIV gave birth.
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In reviewing the chart for your next patient, you note that she is a 28-year-old woman with epilepsy. What information do you need to provide her when it comes to contraceptive choices? Many family planning clinicians encounter this scenario. Epilepsy is one of the most common chronic health conditions affecting reproductive-age women.
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New evidence indicates that women with benign breast disease have a higher risk for breast cancer, and that certain types of breast disease may predict the near-term development of breast cancer.