-
Based on a large national database of heart valve patients, a risk score has been developed to predict operative mortality for any valve surgery.
-
Body size is not a significant predictor of CABG mortality.
-
Recurrent MI a major cause of death in post MI left-ventricular
dysfunction patients.
-
High-risk patients benefit from perioperative beta-blockers when undergoing major noncardiac surgery according to new study.
-
Patients who have had a transient ischemic attack have not only a high short-term chance of ischemic stroke but also a long-term risk of vascular events over 10 years or more.
-
report provides evidence of a drug target polymorphism in epilepsy patients predictive of their maintenance dose of AEDs.
-
A new from of limbic encephalitis is reported, characterized by neuropil antibodies. Patients show an excellent response to immunotherapy or tumor resection.
-
Better understanding of the mechanisms of the IRIS may enable prevention or cure of this severe, sometimes fatal complication of HAART.
-
Neuropathies with IgM monoclonal gammopathy may respond to various chemotherapeutic agents, although the long-term effects are unknown.
-
These 2 cases demonstrate a tragic complication of natalizumab therapy in this promising novel immune modulatory therapy, and the difficulties of predicting late stage drug failures in the difficult and costly process of drug development.