Clinical
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Better Diagnostics Equals Fewer Unnecessary Antibiotic Prescriptions
Researchers credit diagnostic stewardship as the top reason for an impressive reduction in needless antibiotic prescriptions.
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Concerns and Complications of Measles and Mumps and the Increasing Threat of Monkeypox
Measles and mumps, while clinically dissimilar, share important characteristics that are valuable to discuss in tandem. This review will seek to inform the practitioner about current outbreak concerns regarding measles and mumps, clinical manifestations and complications of each, diagnostic and treatment options, and prevention of further exposures. The emerging threat of monkeypox also is discussed.
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Shared Decision-Making Is Ethical Balancing Act for Clinicians
Physicians should always inform, usually recommend, sometimes attempt to persuade — but never manipulate or coerce.
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Dextromethorphan/Bupropion (Auvelity)
Auvelity can be prescribed to treat major depressive disorder in adults.
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Antibiotic Resistance: We Were Doing Great and then COVID Happened
After improvement, antimicrobial resistance in the United States significantly increased.
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Clinical Significance of Mitral Annular Calcification
Researchers found mitral annular calcification to be uncommon, and few experienced associated moderate to severe mitral stenosis or regurgitation. However, the latter group recorded a high mortality rate over three years follow-up, which was significantly lower in those who underwent valve interventions, even when corrected for younger age, fewer comorbidities.
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Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD
This multicenter cohort study found a high incidence of post-traumatic stress disorder symptoms among family members of COVID-19 patients at three months after the index intensive care unit admission.
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Hot Trials from the European Society of Cardiology Annual Congress
Some highlights from two key studies presented in Barcelona, Spain, between Aug. 26 and Aug. 29, 2022, along with Dr. Crawford’s personal commentary on both.
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Importance of Medication Adherence in Ischemic Heart Disease
The results of a subanalysis of the ISCHEMIA trial indicated about one-quarter of patients in both conservative and invasive strategy groups were nonadherent to recommended medical therapy at baseline. Nonadherence was associated with worse health status in both groups at baseline and after one year.
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Ejection Fraction and Outcomes in Bicuspid Aortic Valve Disease
A study of patients with bicuspid aortic valve and moderate or more aortic valve disease revealed the cutpoint for considering aortic valve replacement should be moved from < 50% to < 60% in the guidelines.