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Ovarian cancer patients relapsing within 6 months of their primary therapy represent among the most challenging patients to treat. Generally, in this setting, most patients have only been exposed to one or two agents, yet they are phenotypically resistant to most chemotherapeutics, making drug discovery of paramount importance.
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Richards and colleagues representing the Canadian Multicentre Osteoporosis Study Research Group reported the effect of daily selective serotonin reuptake inhibitors (SSRIs) use in a prospective cohort study in 7 regional centers of 5008 adults over the age of 50.
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High-Dose Statin Therapy, Value for Older Adults; Simvastatin, Best for Parkinson's Disease; Polyethylene Glycol for Chronic Constipation; FDA Actions
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Glass and colleagues from the Kaiser Permanente Northwest Center for Health Research compared breast cancer incidence rates with use of screening mammography and postmenopausal hormone therapy prescriptions between 1980 and 2006.
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Despite an increasing array of methods for control of diabetes, not even half of patients currently have attained and maintain an A1c less than 7%.
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Disturbance of sleep continuity, but not simple sleep deprivation, impairs pain inhibition and increases spontaneous pain.
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Liver fibrosis from chronic hepatitis C is worse after menopause and less severe in women receiving hormone therapy.
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The FDA has approved a humanized monoclonal antibody for the treatment of paroxymal nocturnal hemoglobinuria (PNH).
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After a positive coronary CT scan, patients often undergo stress myocardial perfusion scanning, but the relationship between these two tests in relation to prognosis is poorly understood.