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  • Reduction of Atrial Fibrillation by Pacing Mode

    This paper reports the results of the Search AV Extension and Managed Ventricular Pacing for Promoting Atrioventricular Conduction (SAVE PACe) Trial. This study evaluated the use of pacing algorithms that were designed to minimize the percentage of ventricular pacing in patients with symptomatic sinus-node dysfunction.
  • Off-Pump vs On-Pump CABG

    The effectiveness of off-pump coronary artery bypass graft surgery (OPCAB) is controversial. Thus, Hannan and colleagues from New York evaluated the short-term and long-term results of OPCAB with sternotomy vs on-pump CABG in New York State between 2001-2004.
  • Pharmacology Watch

    Are thiazolidinediones safe? New study shows Zometa reduces risk of hip fractures and improves survival; Merck HIV vaccine proven ineffective in clinical trials; no causal association found between exposure to mercury from thimerosal; and FDA approvals.
  • Revascularization for Stable Coronary Artery Disease

    Exceptional attention has been paid to the recent publication of the COURAGE Trial (April 2007) regarding the efficacy of percutaneous coronary intervention (PCI) in stable coronary disease patients, whereas in acute coronary syndromes, including STEMI and unstable angina, there is reasonable consensus as to an interventional approach in patients with either PCI or CABG as opposed to medical therapy.
  • ECG Diagnosis of Acute Myocardial Infarction

    Although ECG is the standard initial screening test for acute coronary syndromes, its value for the diagnosis of acute myocardial infarction (MI) is difficult to determine because of the vagaries of serum biomarkers.
  • Driving and Parkinson's Disease

    A simple screening test can predict which patients with Parkinson's disease (PD) may have trouble driving a motor vehicle.
  • Not Tonight, Dear! It May Cause a Headache

    Benign headaches associated with sexual activity are either a dull aching pain prior to orgasm or severe pain at orgasm. They can be prevented with indomethacin, beta-blockers, or triptans.
  • Does Warfarin Benefit Offset Hemorrhage Risk in Elderly AF Patients?

    Elderly patients with atrial fibrillation (AF) benefit from warfarin, with a 50% reduction in stroke risk.
  • Clinical Briefs in Primary Care Supplement

  • Pharmacology Watch

    Are thiazolidinediones safe? New study shows Zometa reduces risk of hip fractures and improves survival; Merck HIV vaccine proven ineffective in clinical trials; no causal association found between exposure to mercury from thimerosal; and FDA approvals.