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Orlistat in Overweight Patients with Type 2 Diabetes; Sleep Attacks in Patients Taking Dopamine Agonists; Probiotics in Prevention of AAD; Botulinum Toxin for Wrist and Finger Spasticity; Exercise in People with Fibromyalgia; Risk of Diabetes Among Patients with Schizophrenia
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This study compared the efficacy of several commercially available insect repellents. The topical application of compounds containing DEET was far more protective against mosquito bites than was application of products containing soybean oil or citronella.
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Murine typhus is an unusual infection and probably often overlooked. Outbreaks occur when there is migration of rats and mice into residential areas.
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A clonal outbreak of a newly identified organism, Clostridium neonatale, occurred in association with necrotizing enterocolitis in a neonatal ICU.
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The emergence of chronic wasting disease, a transmissible spongiform encephalopathy in North American cervids, raises concern about potential transmission to humans, as has occurred elsewhere with bovine spongiform encephalopathy and vCJD.
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Serial MRI measurements can be used to map the pattern of regional brain atrophy in a variety of neurologic disease states. Using robust techniques that minimize the subjectivity of morphometric analysis, Scahill and colleagues compared rates and regional distribution of brain atrophy in 4 presymptomatic patients, 10 with mild Alzheimers Disease (AD), 12 with moderate AD, and age-matched controls.
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Metman and associates carried out a controlled trial using amantadine to determine whether they could ameliorate chorea. This was based on prior studies showing that N-methyl-D-aspartate antagonists such as dextrophan, dextromethorphan, and amantadine can alleviate levodopa-induced chorea inpatients with parkinsonism.
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Multiple system atrophy (MSA) is a neurodegerative disorder that can take protean forms. In this elegant paper, Tsuda and colleagues show that patients with the cerebellar form of MSA can be distinguished from idiopathic cerebellar degeneration before other signs of autonomic or parkinsonian disability develop.
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In an extremely preliminary report, Mayer and associates present data on 5 patients with basilar artery thromboses treated with a device called Neuronet.
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While hypertension and smoking have been previously associated with aneurysmal subarachnoid hemorrhage, this is the first report of a role for coffee consumption. The methodology of the study, however, begs several further questions.