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In this pooled analysis of more than 7700 ovarian cancer patients and nearly 12,000 controls, low-dose aspirin and high-dose non-aspirin NSAID use was associated with a risk reduction for invasive epithelial ovarian cancer of 20-34% relative to non-users. Acetaminophen use was not associated with a risk reduction, irrespective of dose or frequency.
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In a large Norwegian population-based cohort study, women with a history of unilateral oophorectomy experienced a slightly earlier onset of menopause compared to women with both ovaries, but this finding does not suggest a clinically important effect.
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A retrospective cohort study of 519 women diagnosed with polycystic ovary syndrome demonstrates that black adolescents and reproductive-aged adults have a higher risk for metabolic syndrome and cardiovascular disease compared to their white counterparts.
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In a large population of older community-dwelling women, there was a strong association between limited motor and balance skills and urge incontinence.
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In this prospective cohort study, women who used the copper IUD for emergency contraception had lower unintended pregnancy rates in the following 12 months compared to women who chose the oral levonorgestrel pill.
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The first article summarizes the practical aspects of choosing an antibiotic in a patient with a reported drug allergy. The second describes the presence of K103 resistant virus in CSF but not in plasma.
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A protease-inhibitor-based regimen containing lopinavir-ritonavir provided more durable antiviral efficacy than a similar regimen containing nelfinavir in treatment-naïve HIV-infected patients.