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The Holy Grail of Diagnosing Depression: An Effective Blood Test
An objective, laboratory based diagnostic tool for depression would be extremely helpful to primary care physicians. This study using nine biomarkers holds promise that a blood test may be able to identify depressed patients among non-depressed primary care patients -
Tedizolid — Formulary Considerations
FDA approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs) caused by susceptible gram-positive organisms including Staphylococcus aureus (MRSA and MSSA), Streptococcus agalactiae, Streptococcus anginosus group, Streptococcus pyogenes, and Enterococcus faecalis. -
Peri-procedural Management of New Oral Anticoagulants
Due to the short half-life and rapid onset of action of the new oral anticoagulants (NOACs), peri-procedural anticoagulant free time intervals should be shorter than with warfarin. Thus, there is uncertainty about the use of heparin bridging. These investigators from Germany analyzed the Dresden NOAC registry data to assess peri-procedural NOAC management and safety until 30 days post-procedure. -
Health Care Utilization in the Aftermath of Severe Sepsis
SYNOPSIS: This observational cohort study of survivors of severe sepsis found that the post-discharge needs of this population are substantial. Severe sepsis survivors spent more days admitted to facilities after their acute hospitalization than prior and had greater mortality, a steeper decline in days at home, and a greater increase in proportion of days alive in a facility compared to survivors of non-sepsis hospitalizations.
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Can We Reduce Unnecessary Head CT Scans in Patients with Delirium?
This study was a retrospective review of medical records of hospitalized general medicine patients with head CT imaging performed for the evaluation of delirium. -
Nasal High-Flow Oxygen Lowers Reintubation Rate
SYNOPSIS: Use of nasal high-flow oxygen was associated with better comfort, fewer desaturations and interface displacements, and a lower reintubation rate.
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The New Guidelines Put C. difficile on the Run
SYNOPSIS: Patients have decreased disease recurrence and mortality when physicians follow the IDSA/Society for Healthcare Epidemiology of America guidelines for the treatment of C difficile infection.
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Outcomes with Worsening Renal Function in Patients with Diastolic Heart Failure
Worsening renal function and outcome in heart failure patients with preserved ejection fraction and the impact of angiotensin receptor blocker treatment. -
Clinical Briefs in Primary Care
Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients with Isolated Systolic Hypertension and LVH; Increase in Nocturnal Blood Pressure and Progression to Microalbuminuria in Type 1 Diabetes; HRT, Lipid, and Glucose Metabolism in Diabetic and Nondiabetic Postmenopausal Women; Effects of Long-Term Treatment With ACE Inhibitors in the Presence or Absence of Aspirin; Long-Term Risks Associated with Atrial Fibrillation: 20-Year Follow-up of the Renfrew/Paisley Study; Olfactory Impairment in Older Adults -
Conferences coming for Contraceptive Technology
Circle your calendar for the upcoming annual Contraceptive Technology Conferences. The San Francisco conference is scheduled for March 12-15, with the Washington, DC, conference set for March 26-29.