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A recent study in patients with fibroids has correlated the size, location, and number of fibroids with the rate of preterm birth, postpartum hemorrhage, need for cesarean section, and fetal size findings that can be useful in counseling patients with fibroids.
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A large prospective cohort study of perineal talc use demonstrated no increased risk of ovarian cancer overall or within any histological subtype. In addition, no association with talc application method was observed.
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According to this pharmacokinetic study, the cyclic use of 20 mcg ethinyl estradiol oral contraceptives is problematic for obese women. Ovarian activity was better suppressed with continuous use (omitting the hormone-free interval) of the same dose oral contraceptive or increasing to a higher dose 30 mcg ethinyl estradiol oral contraceptive
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Polycystic ovarian syndrome patients with normospermic partners undergoing ovulation induction with letrozole had a higher live birth rate and no increase in adverse outcomes than women who received clomiphene citrate.
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In a longitudinal population-based study, metformin use was associated with an increased incidence of low thyroid-stimulating hormone (TSH) levels in patients with treated hypothyroidism.
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This article originally appeared in the November 29, 2014, issue of Internal Medicine Alert. It was edited by Stephen A. Brunton, MD, and peer reviewed by Gerald Roberts, MD. Dr. Brunton is Adjunct Clinical Professor, University of North Carolina, Chapel Hill, and Dr. Roberts is Senior Attending Physician, Long Island Jewish Medical Center, NS/LIJ Health Care System, New Hyde Park, NY.
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Patent foramen ovale (PFO) is common in both the general population, as well as in patients with cryptogenic stroke, with an estimated prevalence somewhere between 15-35%. Recurrent neurovascular events, both recurrent ischemic stroke as well as transient ischemic attacks, are frequent in these patients, but it is not clear whether patients with PFOs have an increased rate of recurrent events compared to those patients who do not have PFOs.
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he Choosing Wisely Campaign was introduced in 2011 by the American Board of Internal Medicine to identify practices and procedures physicians and patients should question. The critical care top 5 list was developed through a collaborative effort of several critical care societies.
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Each year when I lecture the incoming cardiology fellows on the management of non-ST elevation acute coronary syndromes (NSTE-ACS), we embark on a discussion of optimal guideline-driven treatment vs. real-world practicalities.
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This study, done at a tertiary care university hospital here in the U.S., was initiated in an attempt to improve patient safety, conserve a vital resource, and reduce costs a laudable tripartite goal.