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This well-designed two-year trial shows that 1,200 mg daily of calcium citrate in healthy middle-aged men translates into higher bone mineral density and fewer falls, expanding on a body of evidence that had been focused primarily on the use of calcium in women and osteoporosis.
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Genetic research and results are playing an increasingly large role in clinical medicine. I suspect that most physicians are not adequately knowledgeable about genetics; nor am I. At present, the genetics of clopidogrel and warfarin are front and center, as well as an increasing number of genetic studies dealing with normal metabolism, as well as dyslipidemia.
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Nebivolol is a new beta 1 selective blocker with vasodilatation properties via activation of the L-arginine/nitric oxide pathway. Short-term studies, and a long-term, open-label study, have shown excellent efficacy and safety in stages 1-11 hypertension.
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Ray et al examined the computerized files of Tennessee Medicaid recipients to estimate the effects of atypical antipsychotic drugs on the risk of sudden cardiac death.
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The goal of treatment during ST elevation myocardial infarction (STEMI) is early reperfusion of the occluded coronary artery, as this has been shown to reduce mortality and morbidity.
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FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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In this paper, stevenson et al, from 18 centers with expertise in ventricular tachycardia (VT) ablation, report the results of VT ablation using the Thermo°Cool-irrigated, tipped-radiofrequency ablation catheter. Patients were eligible for the study if they had multiple episodes of sustained monomorphic VT that had required either cardioversion or antiarrhythmic drug administration in the previous six months.
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Small studies with older equipment at single centers have shown that coronary CT angiography (CTA) is promising for evaluating coronary anatomy. New 64-slice CT scanners have improved spatial and temporal resolution. Thus, these investigators from the Netherlands conducted a prospective, multi-centered, multi-vendor study to assess the accuracy of 64-slice CTA for in dentifying significant coronary artery disease (CAD) in symptomatic patients undergoing conventional coronary angiography (CCA).
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Preliminary data from this year's flu season indicates that another mismatch may be occurring between this year's vaccine and the predominant circulating strains of influenza A and influenza B viruses.
