-
-
To incorporate evidence-based guidelines into both practice and research, the Research and Development Committee of the International Urogynecological Association embarked on a lengthy process, which included a literature review, creation of recommendations, incorporation of expert consultant opinion, writing a white paper for association members, final revision, and then publication in its journal.
-
The primary objective of the PLCO study is to evaluate the impact of annual screening with transvaginal ultrasound (TVUS) and CA125 on ovarian cancer mortality. The study is prospectively following a cohort of more than 34,000 largely postmenopausal women with intact ovaries with an algorithm where either an abnormal CA125 (e" 35 units/mL) or an abnormality on TVUS is considered a positive screen.
-
Ray et al examined the computerized files of Tennessee Medicaid recipients to estimate the effects of atypical antipsychotic drugs on the risk of sudden cardiac death.
-
This meta-analysis of studies examining the efficacy of systemic corticosteroids for preventing laryngeal edema following extubation concludes that this treatment is effective. This result differs from those of several previous meta-analyses, and raises practical issues such as whether extubation should be delayed for at least 12 hours after a patient passes a spontaneous breathing trial and qualifies for extubation so that a course of steroids can be given.
-
Sleep disordered breathing occurs in most acute stroke patients and may contribute to morbidity
-
Preliminary data indicate that the prevalence of influenza A (H1N1) virus strains resistant to the antiviral medication oseltamivir is high. Therefore, interim guidelines issued by the CDC are to use zanamivir or a combination of oseltamivir and rimantidine if influenza A (H1N1) infection is suspected.
-
Nucleic acid amplification (NAA) testing should be performed on at least one respiratory specimen from each patient with signs and symptoms of pulmonary TB for whom a diagnosis of TB is being considered but has not yet been established, and for whom the test result would alter case management or TB control activities.
-
Individualization of therapy with pharmacogenetics; the rate vs rhythm debate; the FDA's Risk Evaluation and Mitigation Strategy; FDA actions.
-