-
Since the risk of gastrointestinal bleeding is increased when clopidogrel is added to aspirin therapy in patients with acute coronary syndromes (ACS), many prescribe proton-pump inhibitors (PPIs) to reduce this risk. However, mechanistic studies suggest that PPIs may reduce the effectiveness of clopidogrel.
-
Whether oral vitamin K reduces the risk of bleeding related to excessive anticoagulation from warfarin remains unclear.
-
In this study of physician use of clinical information technology in relation to 4 common diagnoses in 41 urban hospitals in Texas, inpatient outcomes were better the more extensive the use of computerized order entry, test results, physician charting, and decision support. Increased use of IT was also associated with significantly lower costs for all hospital admissions.
-
Dronedarone is a new antiarrhythmic drug with structural similarities to amiodarone. During development of the molecule, the steps included removal of the iodine atoms and making the compound more lipophilic; the latter produces a shorter elimination half-life and reduced tissue accumulation.
-
Surveillance data from the CDC show that central-line associated bloodstream infections due to methicillin-resistant Staphylococcus aureus in U.S. intensive care units showed an overall decrease of 50% during 1997-2007.
-
Eligible subjects in this study included all patients with concurrent HIV infection and syphilis in a prospective cohort who had no neurologic symptoms at time of lumbar puncture.
-
Balb/CJ mice infected with influenza virus were superinfected with an antibiotic-susceptible strain of S. pneumoniae and treated intraperitoneally with ampicillin alone, clindamycin alone, ampicillin plus clindamycin, or azithromycin.
-
Patients with lyme arthritis were more likely to have knee involvement (p < 0.001), a history of a tick bite (p = 0.02), and less likely to have a history of fever (p < 0.001) or fever ...
-
Many reports evaluating coronary risk factors in overtly healthy individuals have been highlighted in a variety of preventative cardiology programs, guidelines, and sources. The Framingham Study gave an amazingly powerful kick start to the recognition of coronary risk factors.
-
The U.S. National Registry of Sudden Death in Athletes assembles and analyzes data on the deaths of young athletes who participate in competitive sports.