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Expert Panel Debunks Common Sleep-Related Myths
Authors identified and deconstructed 10 misconceptions parents hold about teenage nocturnal patterns.
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Top Heart Medication Could Help Alcohol Use Disorder Patients
Spironolactone is known to block mineralocorticoid receptors, an action believed to reduce alcohol cravings.
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Irregular Sleep Could Cause More Inflammation
Those who slept few hours per night exhibited troubling signs of improper immune system function in a small study.
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CDC: U.S. Adult Obesity Rate Up Sharply
At least 35% of adults are obese in 19 states and two territories.
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Probiotics and Iron Intake in Pregnant Women
In a randomized, controlled trial, a significantly smaller decrease in serum ferritin was observed in pregnant women with the intake of a Lactinplantibacillus plantarum 299v supplement containing a low dose of iron, folic acid, and ascorbic acid than in the placebo group.
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Measuring the Effect of Ending Food Deserts in Obese Children
A study of New York City students followed for 12 months after the opening/remodeling of a grocery store incentivized to provide healthy food options revealed a small but significant decrease in body mass index scores and a decrease in the likelihood of obesity in the students living within walking distance to the store compared to a control group of peers living farther from such a store.
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Improvement of Memory with Transcranial Electrical Brain Stimulation in Patients with Alzheimer’s Disease
The authors showed that gamma frequency transcranial alternating current stimulation targeting the precuneus in patients with Alzheimer’s disease improved measures of immediate and delayed verbal memory as well as associative memory for faces. Additionally, neurophysiological measurements of cholinergic transmission improved. Apolipoprotein E genotype and baseline cognitive performance were correlated with treatment response. Memory improvement was correlated both with increases in gamma frequency power in posterior cortical regions and spatial overlap between the modeled electric field distribution and the precuneus target site.
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Magnetic Resonance Imaging Evaluation of Perivascular Space Abnormalities in Neuromyelitis Optica
Perivascular space (PVS) abnormalities were demonstrated in two cohorts of patients with neuromyelitis optica spectrum disorder (NMOSD) as compared to healthy controls. Magnetic resonance imaging provided visualization of PVS enlargement, and quantification of reduced flow in NMOSD patients, both of which were found to be associated with disease outcomes.
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COVID-19 Vaccination in Patients with Autoimmune Neuromuscular Diseases
In a population-based, self-reporting survey of patients with immune-mediated myopathy and myasthenia gravis, the frequency of both mild and severe acute adverse events appeared to be no more frequent than in the general population. COVID-19 vaccinations are safe for this population of patients.
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Benefits and Risks of Dual Antiplatelet Therapy After Acute Ischemic Stroke or TIA
Secondary prevention of acute ischemic stroke is continuing to evolve with great interest in the use of dual antiplatelet treatment early in the course. A complicating factor has been the role of the CYP2C19 loss-of-function gene that interferes with the conversion of clopidogrel to its active antiplatelet metabolite.