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  • Screening for Ovarian Cancer: One

    Successful screening for ovarian cancer, the gynecologic malignancy with the highest case to fatality ratio, has been elusive due to the low prevalence of disease in the general population and the high cost for modalities needed to produce testing specificity acceptable for routine use. The UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) was designed to definitively assess the effect of ovarian cancer screening on mortality, as well as, to comprehensively address the cost, acceptance, physical and psychosocial morbidity, and performance characteristics of multimodal screening (MMS) and ultrasound-based screening (USS).
  • The Role of Folic Acid Fortification in Preventing Fetal Cardiac Defects

    The medical community has been well aware of the importance of adequate intake of folic acid in the prevention of neural tube defects (NTDs). However, less attention has been given to its role in the development of the fetal heart.
  • Do Statistics Ever Lie?

    I hate statistics. I don't understand statistics. Statistics are so confusing. How many times have these statements (or something like them) crossed your lips? I know that I certainly feel that way sometimes.
  • To Save or Not to Save the Ovaries: The Mayo Clinic Study

    The Mayo Clinic Cohort Study of Oophorectomy and Aging included 1274 premenopausal women with unilateral oophorectomy (followed for a median of 29.5 years) and 1091 premenopausal women with bilateral oophorectomy (followed for a median of 25 years) who had surgery from 1950 through 1987, compared with 2383 matched women from the same population of women who had not undergone oophorectomy.
  • Pharmacology Watch

    NSAIDs in the elderly; managing GI and CVD risk with NSAIDs; low-dose naltrexone and fibromyalgia; treating glucocorticoid-induced bone loss; FDA Actions.
  • Artemether and Lumefan-trine Tablets (Coartem®)

    The FDA has approved a new drug combination for acute, uncomplicated malaria infection.
  • Colorectal Screening and Advancing Age

    Advancing age was inversely related to the frequency of colorectal cancer screening, but even severe comorbidity did not seem to proportionally decrease colorectal cancer screening.
  • ECG Review: And If the Patient Had Chest Pain?

    The ECG above was obtained from a 62-year-old man with hypertension who was being seen in the office. How would you interpret this tracing if he had told you of some chest discomfort that he felt for the first time earlier that morning?
  • Clinical Briefs By Louis Kuritzky, MD

    Weight management issues continue to be problematic for persons with type 2 diabetes.
  • Choosing a Fecal Occult Blood Test

    Correlation of 6 different immunochemical qualitative fecal occult blood tests with colonoscopy findings showed wide variation in diagnostic performance.