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Medication Therapy Management: Partnering with Clinical Pharmacists to Improve Patient Outcomes
The majority of American adults have at least one chronic disease, often requiring the use of multiple chronic medications. Unfortunately, adherence to chronic medications often is suboptimal, leading to inadequate management of chronic conditions and the risk for morbidity and mortality. This review discusses the foundation of medication therapy management, a service that pharmacists and other healthcare professionals provide to optimize therapeutic outcomes via a patient-centered approach.
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Bexagliflozin Tablets (Brenzavvy)
Bexagliflozin can be prescribed as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
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Do Spinal Cord Stimulators Really Help for Chronic Pain?
The results of a comprehensive analysis of a large clinical database regarding treatment of patients with chronic low back pain did not support the benefit of spinal cord stimulators compared to conventional medical management for chronic pain.
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Magnetic Brain Stimulation for Alzheimer’s Disease
Transcranial magnetic stimulation, targeted at the precuneus to help maintain a normal default mode network, shows some promise in slowing cognitive decline and maintaining normal electrophysiology in patients with mild to moderate Alzheimer’s disease.
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Ablation vs. Drug Therapy for Atrial Fibrillation, Revisited
A three-year follow-up of EARLY-AF, a study of relatively young and healthy patients with recent atrial fibrillation, showed cryoablation remains superior to drug therapy for preventing the development of persistent atrial fibrillation.
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An Easy Measure of Potentially Harmful Salt Intake
Those who rarely or never added salt to their food and strongly adhered to the Dietary Approaches to Stop Hypertension diet exhibited the lowest incidence of subsequent cardiovascular disease.
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Novel Bedside Procedure Improves Tracheostomy Outcomes
Nurse-driven initiative led to zero incidents of tracheostomy medical device-related pressure injuries for three years.
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Effectiveness of Dietary Supplements on Lipid and Inflammatory Biomarkers
In a comparison of rosuvastatin 5 mg/day, six common dietary supplements marketed for improving heart health, and placebo, none reduced high-sensitivity C-reactive protein levels. Only rosuvastatin significantly reduced LDL cholesterol levels compared to placebo.
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Long-Term Maintenance Therapy After Percutaneous Coronary Intervention
An extended six-year follow-up of the HOST-EXAM study revealed the consistent benefit of the primary endpoint of fewer major cardiovascular events and less bleeding with clopidogrel vs. low-dose aspirin monotherapy in post-percutaneous coronary intervention patients who were on dual antiplatelet therapy for one year.
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How to Diagnose ATTR Cardiac Amyloidosis
A retrospective study of patients with confirmed cardiac amyloidosis showed negative light chain biomarkers and a typical pattern of cardiac amyloid on cardiac MRI was highly specific for the diagnosis of the transthyretin subtype and may obviate the need for further testing before starting treatment.