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  • Hepatocyte Apoptosis in Hepatitis C/HIV Co-Infection

    This interesting paper from Groopman's laboratory at Beth Israel in Boston, reports the results of some elegant experiments designed to elucidate potential mechanisms, accounting for the innocent bystander hepatocyte apoptosis previously observed as a result of binding of HCV and HIV proteins.
  • CDAD: Novel Therapeutics

    Lagrotteria and colleagues enrolled 39 inpatients with a primary episode of Clostridium difficile-associated diarrhea (CDAD) to receive treatment for 10 days with either metronidazole (MET) alone or together with rifampin (RIF).
  • Darunavir (TMC114) Approved by the FDA

    Darunavir (known during development as TMC114 and given the proprietary name, PREZISTA-TM) was approved by FDA on June 23, 2006, for use in combination with other antiretroviral agents for the treatment of HIV infection in adults.
  • Cluster Headaches

    Cluster headache may be accompanied by a variety of neurological manifestations, and responds well to triptans and oxygen therapy.
  • Cancer or Heart Disease? Drinkers May Need to Choose

    Moderate alcohol intake was associated with longer survival and better quality of life scores for Australian women age 70-75 years old, while non-drinkers had greater risk of death and poorer health-related quality.
  • Clinical Briefs By Louis Kuritzky, MD

    In the United States, COPD is the 4th leading cause of death. Widespread public education about smoking toxicity has not decreased COPD mortality, and since 2000 the number of women who die from COPD has eclipsed men.
  • Posaconazole Oral Suspension (Noxafil®)

    The FDA has approved a new antifungal agent for the prevention of Aspergillus and Candida infections in at-risk individuals. Posaconazole is an oral triazole, broad spectrum, antifungal chemically similar to itraconazole.
  • The Nose Knows

    People who have symptoms of allergic rhinitis report more sleep complaints, including daytime sleepiness, than do those without allergic rhinitis.
  • Exercise and Restless Legs Syndrome

    A program of resistive exercise and treadmill walking reduced the severity of restless legs syndrome symptoms.
  • Clinical Briefs in Primary Care supplement

    What is the Best Way to 'Predict' Diabetes: IFG, IGT, or A1c?; Hair Growth With Finasteride: Not Just More, but More Better!; Prevalence of Diabetic Neuropathy; Hypogonadism is Surprisingly Common in Middle-Aged Men; Carpal Tunnel Syndrome: Capturing the Benefits of MultiModal Treatment; Diastolic Dysfunction: Not So Benign