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In a randomized trial comparing immediate radiation therapy to delayed treatment in patients who underwent primary surgical resection of low-grade gliomas, overall survival was not significantly different between the 2 groups.
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The probability of in-hospital death was higher for patients with the lowest total FOUR score than for those with the lowest total GCS score.
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There is a role for endovascular therapy, such as stenting, as reported in Stroke, in the setting of failed medical management with anticoagulants.
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Bacterial resistance to antibiotic treatment has concerned the medical community since the introduction of the first antibiotics in the 1920s. Development of new anti-infective agents has been precipitated by increasing resistance to older agents and classes of agents. While high rates of resistant organisms have been particularly problematic in hospital intensive care units, serious resistance now is being encountered in community-acquired infections. This review will focus on the clinical aspects of antibiotic resistance in community-acquired respiratory infections, pharyngitis, skin infections, and urinary tract infections.
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The role of primary tumor resection for those who present with disseminated breast cancer has not been established. Rapiti and colleagues performed a population-based study to determine the impact of local surgery on survival in women with breast cancer who, at the time of initial presentation, were known to have distant metastases.
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For years clinicians have been administering oxygen by mask to patients with worrisome fetal heart rate patterns. Yet, a Cochrane database review has questioned this practice because of the lack of solid date to demonstrate its benefit.
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New Hope for Macular Degeneration?; Can Cialis be Used for Edema?; FDA Actions
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Despite the grim statistics, recurrent ovarian cancer is somewhat distinguished from other solid tumors in its ability to retain and regain some "sensitivity" to chemotherapy long into its natural progression.
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In a prospective, randomized trial, both norethindrone 1 mg/ethinyl estradiol 35 mg taken three times a day initially as well as medroxyprogesterone acetate 20 mg t.i.d. initially were comparably effective and reasonably well tolerated.