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Aortic stenosis increases the risk of MI, but not overall mortality with noncardiac surgery.
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QRS duration does not predict occurrence of VT or VF necessitating ICD therapy.
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Left atrial remodeling in competitive athletes may be regarded as a physiologic adaptation to exercise conditioning, largely without adverse clinical consequences.
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Arrhythmia is the primary problem rather than a marker of an underlying cardiomyopathy.
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In patients presenting with high-risk STEMI, TNK plus immediate angioplasty reduced the risk of recurrent ischemic events compared with TNK alone and was not associated with an increase in major bleeding complications.
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More recent trials, and meta-analyses of all trials, have shown a reduction in death and myocardial infarction (MI) with a routine invasive strategy vs an ischemia or symptom-driven invasive strategy over 6-24 months for patients with non-ST elevation (E) acute coronary syndrome (ACS). However, an increase in death during the initial hospitalization in the routine invasive arm makes long-term outcome data important. Thus, the British Heart Foundation RITA 3 trial 5-year data are of interest.
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Introduction of HAART has dramatically modified the natural history of HIV disease by controlling viral replication, but, in turn, lengthening of the survival of HIV-infected individuals has been associated with an increasing prevalence of iatrogenic conditions.
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Dopamine neuronal replacement cell therapy can be beneficial for patients with advanced disease, and that changing technical approaches could have a favorable impact on efficacy and adverse events following neural transplantation.
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Successful treatment of SDB, which is frequently associated with chronic sleepwalking, controlled the syndrome in young adults.
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In a randomized trial of neurosurgical clipping versus endovascular coiling for ruptured intracranial aneurysms, endovascular coiling was more likely to result in independent survival at 1 year.