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  • Acetaminophen Toxicity

    Acetaminophen (known as paracetamol outside the United States) is the most commonly used analgesic in the world, usually considered to be safe and benign.
  • Hypertension

    The Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure is currently updating its work in JNC-7 in an effort to help physicians provide safe, effective, and patient-centered care for those with elevated blood pressure.
  • The Next Influenza Pandemic: Not If, but When

    Avian influenza has created an economic disaster in parts of Asia. While the number of associated identified human infections has, to date, not reached 100 cases, the possibility of a public health disaster looms since the outbreak of avian influenza may be setting the stage for the next human influenza pandemic.
  • Pharmacology Watch: Treating Opioid-Dependent Patients with OAT

    Long-Term Effects of Warfarin Use; Statins Multiple Benefits; FDA Actions
  • Updates by Carol A Kemper

    Following the tragedy on the Jamarat Bridge at Hajj in January 2006, many travel advisors felt the need to re-double their efforts in providing better travel advice. While it is widely acknowledged that this advice is inconsistently followed, this recent tragedy, and the rise of adventure travel, especially among younger travelers, raises an interestingÀ
  • Of Mice and Men and Streptococci

    Microbiologists have been trying for years to make an effective vaccine against infections caused by the Group A Streptococcus (GAS). The best hope has been a vaccine that targets the outer carbohydrate (CHO) coat, since antibodies to these antigens increase with age and there is less GAS disease as humans age.
  • Clinical Briefs in Primary Care supplement

  • That Which Bends Up

    More than 5000 people in the Comoros Islands, off the eastern coast of Africa and near Madagascar, became ill with high fever and severe joint paints in the first months of 2005.
  • An Upgraded Blood Test That Identifies Tuberculous Infection

    Tuberculin skin testing is a crude procedure, fraught with potential error at every step, from application to interpretation, and requires 2 visits to a health care provider. Its use has persisted, nonetheless, because it remained, until recently, the only means of detection of latent infection with Mycobacterium tuberculosis.
  • Abacavir/Tenofovir- and Didanosine/Tenofovir-Regimens

    The first article reports the results of an industry-sponsored clinical trial comparing TDF/ABC/3TC vs EFV/ABC/3TC in treatment-naïve patients. Three hundred forty patients were randomized. Baseline characteristics including CD4 count and HIV RNA level were similar between the arms.