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Investigators have discontinued the FEM-PrEP study of oral emtricitabine and tenofovir disoproxil fumarate (Truvada, Gilead Sciences, Foster City, CA) to prevent HIV infection in women in Africa after interim results indicated the research would be unlikely to prove effectiveness in the study population.
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The Food and Drug Administration (FDA) and the Federal Trade Commission have issued a joint call to remove products from the market that make unproven claims to treat, cure, and prevent sexually transmitted diseases (STDs).
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Results of a new study indicate patients who have tested positive for herpes simplex virus type 2 (HSV-2) but don't have symptoms or genital lesions still experience virus shedding during subclinical episodes.
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COPD in Never Smokers; Early Prostate Cancer: Prostatectomy vs Watchful Waiting; Dietary Vitamin D and Incident Diabetes; Functional Cobalamin Deficiency in Diabetes; Should Leukotriene Antagonists Have Higher Priority for Asthma Control?; Selenium Impacts Orbitopathy in Graves Disease;
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Forty-four (23%) of 192 adventure race participants in a 2005 Florida event developed suspected leptospirosis, with confirmatory serologic testing positive in 45% of the tested individuals. A unique serovar (related to species Leptospira noguchii) was isolated from 1 patient.
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This retrospective study of more than 7000 patients from four combined medical-surgical ICUs demonstrated that ionized calcium levels are unrelated to mortality over a broad range of values but are independent predictors of mortality when levels are severely increased or decreased.
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In assessment of acute chest pain in the emergency room, a new or "presumably new" left bundle branch block (LBBB) is considered as an electrocardiographic (ECG) equivalent to ST elevation.
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Involving family members in ICU rounds improved satisfaction in some areas, such as physician communication and decision-making support, but failed to improve overall family satisfaction.
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In a hospital with high ICU bed occupancy, delays in transferring critically ill patients from the emergency department or general wards to the ICU were associated with increased mortality in comparison with immediate transfer to an ICU bed, and this increased mortality was incrementally greater with increasing delay.
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Current guidelines recommend hypothermia for comatose survivors of out-of-hospital cardiac arrest in whom return of circulation has been achieved.